Table 5b. Equivalent total doses for treatment regimens, for tumour effects and normal tissue effects, if 2 Gy daily fractions would be useda.
| Equivalent total dose with 2 Gy daily fractionation | 25 Gy (10 × 2.5 Gy) | 25 Gy (5 × 5 Gy) | 50 Gy (25 × 2 Gy) | 45 Gy (25 × 1.8 Gy) | 50.4 Gy (28 × 1.8 Gy) |
|---|---|---|---|---|---|
| Tumour, α/β=10 OTT disregarded (Gy) | 26 | 32 | 50 | 44 | 50 |
| Tumour, α/β=10 OTT taken into account (Gy) | 34 | 42 | 50 | 42 | 48 |
| Normal tissue, α/β=5 (Gy) | 26 | 36 | 50 | 44 | 50 |
| Normal tissue, α/β=3(Gy) | 28 | 40 | 50 | 44 | 48 |
a
For calculations see Appendix A. OTT: overall treatment time (days). For calculations disregarding and taking into account OTT, respectively, see Appendix A.
α/β: the linear quadratic quotient, set to 10 for tumour effects; set to 5 and 3 for normal tissue effects. Gy10 (Gy5 and Gy3): the biologically effective dose calculated using an α/β of 10 (5 and 3); Equivalent total dose with 2 Gy daily fractions: the equivalent total dose, if 2 Gy daily fractions would be used, calculated using the linear quadratic formula with α/β quotients as indicated. Results rounded to multiples of 2 Gy fractions.