Table 2. IC50 values (μM) of PTX and NK105 in various cell lines.
| Cancer | Cell line |
48 h
|
72 h
|
||
|---|---|---|---|---|---|
| NK105 | PTX | NK105 | PTX | ||
| Oesophageal cancer | TE-1 | >1.0 | >1.0 | 0.01 | 0.02 |
| TE-8 | 0.02 | 0.02 | 0.01 | 0.01 | |
| Lung cancer | PC-14 | 0.01 | 0.01 | 0.01 | 0.01 |
| PC-14/TXT | 0.15 | 0.09 | 0.08 | 0.06 | |
| H460 | ND | ND | 0.03 | 0.01 | |
| Breast cancer | MCF-7 | >1.0 | >1.0 | 0.01 | 0.01 |
| Stomach cancer | MKN-28 | 0.03 | 0.03 | 0.01 | 0.21 |
| MKN-45 | 0.02 | 0.07 | 0.01 | 0.02 | |
| Colon cancer | DLD-1 | 0.95 | 0.26 | 0.29 | 0.20 |
| HT-29 | 0.01 | 0.01 | 0.01 | 0.01 | |
| HCT116 | ND | ND | 0.03 | 0.01 | |
| Ovarian cancer | MCAS | 0.01 | 0.01 | 0.01 | 0.01 |
| OVCAR-3 | >1.0 | >1.0 | >1.0 | >1.0 | |
| Pancreatic cancer | AsPC-1 | ND | ND | 0.02 | 0.02 |
| PAN-9 | ND | ND | 0.03 | 0.02 | |
| PAN-3 | ND | ND | 0.010 | 0.004 | |
PTX=paclitaxel; ND=not done.