Table 5. Genes the expression levels of which differed significantly in the early invasive carcinoma group and the protruded-type (28 genes) or flat-type (18 genes) adenoma group (Mann-Whitney U-test).

Gene name	Accession no.	P-value		P-value
BMP-4	D30751	0.6128		0.2968
Cdc42	M57298	0.001	CA<AD (P)	0.0122	CA>AD (F)
c-jun	J04111	<0.0001	CA>AD (P)	0.0135	CA>AD (F)
E1AF	D12765	0.0086	CA>AD (P)	0.13
ECGF1	M63193	<0.0001	CA>AD (P)	0.0002	CA>AD (F)
Egr-2	X53700	<0.0001	CA<AD (P)	0.3423
Eph	M18391	0.0005	CA<AD (P)	0.7903
Erk1	X60188	<0.0001	CA>AD (P)	0.0276	CA<AD (F)
FAK	L13616	0.0304	CA>AD (P)	0.4033
GAK	D88435	0.0227	CA<AD (P)	<0.0001	CA<AD (F)
Galectin-1	J04456	0.704		0.0027	CA>AD (F)
Gp130	M57230	<0.0001	CA<AD (P)	0.9093
GST-II	U77604	<0.0001	CA<AD (P)	0.8197
GSTP1	X06547	<0.0001	CA>AD (P)	0.0006	CA>AD (F)
HLA-DQ	U77589	0.1489		0.0682
IGF-2	M29645	0.0034	CA>AD (P)	0.5937
iNOS	AB022318	0.0402	CA>AD (P)	0.0098	CA>AD (F)
Laminin β-3	D37766	0.0016	CA>AD (P)	0.0001	CA<AD (F)
MDR1	AF016535	<0.0001	CA<AD (P)	0.4941
MMP-15	Z48482	0.025	CA>AD (P)	0.0627
MUC-2	M74027	0.0044	CA<AD (P)	0.0334	CA<AD (F)
Mucin 3	AF143371	<0.0001	CA>AD (P)	0.0227	CA<AD (F)
nm23	X17620	<0.0001	CA>AD (P)	0.0001	CA>AD (F)
p120	AF062324	<0.0001	CA<AD (P)	0.4941
p21	U03106	0.7324		0.0402	CA<AD (F)
PMS1	U13695	0.0044	CA<AD (P)	0.0002	CA<AD (F)
Ras-GAP	AF051311	<0.0001	CA<AD (P)	0.7324
Rho 8	X95282	<0.0001	CA<AD (P)	0.8494
Rho GDIβ	L20688	<0.0001	CA>AD (P)	0.0304	CA>AD (F)
Smad4	U44378	<0.0001	CA>AD (P)	<0.0001	CA>AD (F)
TIMP1	X03124	<0.0001	CA>AD (P)	0.0024	CA>AD (F)
αN-catenin	M94151	0.0014	CA<AD (P)	0.0151	CA<AD (F)

CA=early invasive carcinoma group; AD (P)=protruded-type adenoma group; AD (F)=flat-type adenoma group.