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. 2005 Apr 20;92(8):1430–1441. doi: 10.1038/sj.bjc.6602487

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Copyright © 2005 Cancer Research UK

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Combination of HGS-ETR1 with chemotherapeutic agents enhances tumour cell killing in vitro. HCT116, H460, ES2, and TTn cells were plated in 96-well plates at approximately 1 × 10⁴ cells well⁻¹ and cultured overnight. Indicated concentrations of HGS-ETR1 (closed circles), isotype control antibody (IC mAb, open upward triangles); HGS-ETR1 plus indicated chemotherapeutic drug (closed squares), or IC mAb plus chemotherapeutic drug (open downward triangles) were added and cell viability, measured as relative light units (RLU), was determined after 48 h of treatment. Data are the mean±s.d. of triplicate samples.