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. 2005 Apr 20;92(8):1499–1505. doi: 10.1038/sj.bjc.6602515

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Copyright © 2005 Cancer Research UK

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The protrusions on the surface of melanocytes correspond to actin-associated vesicles. The AFM topograph (A; height range: 4.3 μm) and corresponding phase-contrast image (B) of melanocytes treated with FITC-phalloidin show that some of the protrusions observed in the AFM topograph correspond to vesicles. Additionally, the LSCM image (C; optical slice: 0.8 μm) shows brighter actin staining at a fraction of the corresponding points. The AFM image was recorded in the trace scan direction.