Table 1. Expression of α6, αv, β1 and β4 integrins and uPA and uPAR in ovarian cancer and HOSE cells in response to ascites.
Antigen expression (MIF) | OVHS 1 | PEO.36 | OVCA 433 | HEY | HOSE 80 |
---|---|---|---|---|---|
α6 integrin | |||||
−as | 67±6 | 1028±112 | 204±3 | 346±50 | 88±10 |
+as | 176±24 | 1343±52 | 405±50 | 542±78 | 90±12 |
αv integrin | |||||
−as | 90±8 | 67±8 | 53±6 | 120±8 | |
+as | 88±10 | 72±8 | 48±2 | 90±4 | ND |
β1 integrin | |||||
−as | 135±11 | 281±10 | 2308±88 | 1298±20 | |
+as | 171±4 | 345±14 | 2147±28 | 1516±80 | ND |
β4 integrin | |||||
−as | 5±0 | 10±0 | 20±0 | 5±0 | |
+as | 5±0 | 10±0 | 18±0 | 5±0 | ND |
uPA | |||||
−as | 10±0 | 5±0 | 12±0 | 28±4 | 10±0 |
+as | 12±0 | 4±0 | 26±2 | 100±12 | 12±0 |
UPAR | |||||
−as | 12±0 | 5±0 | 12±0 | 34±15 | 10±0 |
+as | 15±0 | 6±0 | 24±1 | 70±28 | 8±0 |
MIF=mean intensity of fluorescence; as=ascites; ND=not determined. The values are ±s.e.m. of experiments repeated with three different ascites. uPA=urokinase plasminogen activator; uPAR=urokinase plasminogen activator receptor.