Table 1. Summary of the clinical parameters and gene alterations of the post-Chernobyl and sporadic papillary thyroid carcinomas studied.
| Sample name | Age | Sex | Tumour size (cm) | Histological variant of PTC | Genotype | Regional LN metastasis | Distant metastasis |
|---|---|---|---|---|---|---|---|
| Post-Chernobyl | |||||||
| ch155 | 12 | F | 2.5 | Solid | RET/PTC3 | + | − |
| ch104 | 12 | M | 4.5 | Papillary | RET/PTC3 | + | − |
| ch163 | 11 | M | 4.5 | Follicular | neg | + | − |
| ch12 | 14 | F | 2 | Solid | RET/PTC3 | + | + |
| ch70 | 18 | F | 5.5 | Papillary | neg | + | + |
| ch109 | 13 | F | 7 | Papillary | RET/PTC1 | + | − |
| ch123 | 13 | F | 5 | Follicular | neg | + | + |
| chs405 | 16 | F | 3 | Papillary | RET/PTC | + | − |
| ch414 | 33 | F | 2.5 | Follicular | neg | − | − |
| chs420 | 28 | F | 1.4 | Follicular | neg | − | − |
| chs422 | 31 | M | 0.9 | Follicular | BRAFT1796A | + (few cells) | − |
| chs423 | 22 | F | 4.5 | Papillary | neg | − | − |
| Sporadic: | |||||||
| p1 | 51 | M | 2.5 | Follicular | RET/PTC | + | − |
| p2 | 49 | M | 0.4 | Papillary | ND | − | − |
| p3 | 59 | M | 6 | Papillary | neg | + | − |
| p4 | 62 | M | 1 | Papillary | BRAFT1796A | NA | NA |
| p5 | 45 | F | 3 | Follicular | BRAFT1796A | − | − |
| p6 | 37 | M | 5 | Papillary | ND | + | − |
| p11 | 37 | F | 1.5 | Papillary | neg | + | − |
| p14 | 32 | M | 1.9 | Follicular | RET/PTC | − | − |
NA=not available; ND=not determined; neg=neither RET/PTC rearrangement nor BRAF mutation.