Table 3. Changes of hormone levels between first and third trimesters by racial groups and the significance of the changes between racial groupsa.
White mothers (n=150)
|
Black mothers (n=150)
|
White mothers vs black mothers | |||
---|---|---|---|---|---|
Hormones | Meanb | P-value | Meanb | P-value | P-valuec |
Alphafetoprotein | 3.3 | <0.01 | 3.0 | <0.01 | <0.01 |
Total estradiol | 2.1 | <0.01 | 2.0 | <0.01 | 0.11 |
Free estradiol | 1.6 | <0.01 | 1.5 | <0.01 | 0.02 |
Free and albumin-bound estradiol | 1.6 | <0.01 | 1.5 | <0.01 | 0.02 |
Total estriol | 2.7 | <0.01 | 2.6 | <0.01 | 0.30 |
Total testosterone | 0.2 | <0.01 | 0.3 | <0.01 | 0.36 |
Free testosterone | −0.5 | <0.01 | −0.4 | <0.01 | 0.36 |
Free and albumin-bound testosterone | −0.5 | <0.01 | −0.4 | <0.01 | 0.36 |
Sex hormone binding globulin | 0.8 | <0.01 | 0.8 | <0.01 | 0.98 |
Ratios | |||||
Total estradiol/total testosterone | 1.9 | <0.01 | 1.7 | <0.01 | 0.01 |
Free estradiol/free testosterone | 2.1 | <0.01 | 1.9 | <0.01 | 0.01 |
Free and albumin-bound estradiol/free albumin-bound testosterone | 2.1 | <0.01 | 1.9 | <0.01 | 0.01 |
Matched analyses.
Means of the differences of the natural logarithm of hormone levels.
Adjusted for gestational age at blood draw (continuous) and maternal weight at pre-pregnancy and delivery (continuous).