Table 4. Number of cycles with grade 1 side effects from BNP7787.
| Stage I | Stage I | Stage II | |
|---|---|---|---|
| 4.1–34.5 g/m2 | 41.0 g/m2 | 18.4 g/m2 | |
| Side effect | (78 cycles) | (26 cycles) | (62 cycles) |
| Hot flushes or warm feeling | 2 | 10 | 1 |
| Dry mouth or bad taste | 2 | 6 (1 grade 2) | |
| Headache | 1 | 10 | |
| Dizziness | 2 | 11 | |
| Hypotension | 2 | ||
| Perspiration | 1 | ||
| Myalgia | 1 | ||
| Nausea | 1 (1 grade 2) | 7 (5 grade 2) | |
| Vomiting | 8 (4 grade 2) | ||
| Abdominal pain | 1 (1 grade 2) | ||
| Vigors | 1 | ||
| Fatigue | 2 | ||
| Pain chest | 1 | ||
| Paresthesias | 1 | ||
| Local i.v. site discomfort | 9 (4 grade 2) | 10 (2 grade 2) | 1 |
BNP7787=disodium 2,2′-dithio-bis-ethane sulphonate; i.v.=intravenous.