Table 2. Risk of breast cancer according to types of antibiotics.
|
Cases
|
Controls
|
||||||
|---|---|---|---|---|---|---|---|
| Type of antibiotic | No. | % | No. | % | OR | 95% CI | |
| Penicillins | Overall | 1974 | 72.4 | 19 589 | 71.8 | 1.00 | 0.91–1.10 |
| More than 10 prescriptions | 204 | 7.5 | 2087 | 7.7 | 0.94 | 0.80–1.12 | |
| Cephalosporinsa | Overall | 1 | 0.0 | 24 | 0.1 | 0.41 | 0.06–3.01 |
| More than 10 prescriptions | 0 | — | 6 | 0.0 | — | — | |
| Macrolides | Overall | 891 | 32.7 | 8381 | 30.7 | 1.07 | 0.98–1.17 |
| More than 10 prescriptions | 22 | 0.8 | 260 | 1.0 | 0.85 | 0.55–1.31 | |
| Tetracyclines | Overall | 344 | 12.6 | 3202 | 11.7 | 1.05 | 0.93–1.19 |
| More than 10 prescriptions | 11 | 0.4 | 73 | 0.3 | 1.44 | 0.76–2.73 | |
| Quinolones | Overall | 195 | 7.2 | 1828 | 6.7 | 1.02 | 0.88–1.19 |
| More than 10 prescriptions | 4 | 0.1 | 35 | 0.1 | 1.05 | 0.37–2.95 | |
| Sulphonamides | Overall | 818 | 30.0 | 8468 | 31.0 | 0.92 | 0.84–1.00 |
| More than 10 prescriptions | 22 | 0.8 | 285 | 1.0 | 0.68 | 0.44–1.06 | |
a
In Denmark, cephalosporins are almost solely used in hospitals.