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. 2005 Feb 1;92(3):488–498. doi: 10.1038/sj.bjc.6602301

Table 5. Late bladder and bowel toxicity (RTOG scoring) by dose and margin randomisations. Maximum toxicity in first 2 years.

  No. (%) of men with toxicity score
  64 Gy dose (N=63) 74 Gy dose (N=61) 1.0 cm margin (N=62) 1.5 cm margin (N=62) All Patients (N=124)
Bowel toxicity
 Grade 0 30 (48) 20 (39) 33 (53) 17 (27) 50 (40)
 1 26 (41) 27 (44) 21 (34) 32 (52) 53 (43)
 2 7 (11) 11 (18) 8 (13) 10 (16) 18 (15)
 3 0 3 (5) 0 3 (5) 3 (2)
 4 0 0 0 0 0
  P=0.02 P=0.005  
           
Bladder toxicity
 Grade 0 33 (52) 24 (39) 29 (47) 28 (45) 57 (46)
 1 23 (37) 26 (43) 27 (44) 22 (35) 49 (40)
 2 5 (8) 8 (13) 5 (8) 8 (13) 13 (10)
 3 2 (3) 3 (5) 1 (2) 4 (6) 5 (4)
 4 0 0 0 0 0
  P=0.17 P=0.27