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. 2005 Feb 1;92(3):547–552. doi: 10.1038/sj.bjc.6602375

Table 1. 17β-Hydroxysteroid dehydrogenase (17HSD) types 1 and 2 expression and the 17HSD2/17HSD1 ratio in relation to tumour characteristics and tamoxifen treatment.

  17HSD1
17HSD2
HSD2/HSD1
  <2.3 >2.3 <0.28 >0.28 <0.2 >0.2
  n=171 n=59 n=175 n=55 n=154 n=76
Lymphnode status/tumour size (mm)
 N−, >20 48 (75) 16 (25) 47 (73) 17 (27) 39 (61) 25 (39)
 N+, ⩽20 50 (72) 19 (28) 55 (80) 14 (20) 53 (77) 16 (23)
 N+, <20 68 (77) 20 (23) 66 (75) 22 (25) 54 (61) 34 (39)
 
ER status
 ER− 36 (71) 15 (29) 42 (82) 9 (18) 36 (71) 15 (29)
 ER+ 135 (75) 44 (25) 133 (74) 46 (26) 118 (66) 61 (34)
 
PgR status
 PR− 67 (73) 25 (27) 73 (79) 19 (21) 65 (71) 27 (29)
 PR+ 104 (75) 34 (25) 102 (74) 36 (26) 89 (64) 49 (36)
 
Tamoxifen
 TAM 2 years 74 (64) 41 (36) 81 (70) 34 (30) 76 (66) 39 (34)
 TAM 5 years 97 (84) 18 (16) 94 (82) 21 (18) 78 (68) 37 (32)