Table 4.
Fatty acid composition of brain phosphatidylinositol from Aldh5a1+/+ and Aldh5a1−/− mice
| PtdIns mole % | Aldh5a1+/+ | Aldh5a1−/− | ||
|---|---|---|---|---|
| FAME | Mean | SD | ||
| 16:0 | 12.2 | 1.7 | 13.9 | 2.8 |
| 18:0 | 37.5 | 1.4 | 37.9 | 4.1 |
| 18:1 n-9 | 6.2 | 0.5 | 6.0 | 0.2 |
| 18:1 n-7 | 2.9 | 0.5 | 2.5 | 0.4 |
| 20:4 n-6 | 34.9 | 2.2 | 29.5 | 4.0* |
| 22:4 n-6 | 1.9 | 0.6 | 2.1 | 0.7 |
| 22:6 n-3 | 3.4 | 0.8 | 4.2 | 0.5 |
| sat | 49.7 | 1.5 | 51.9 | 4.7 |
| unsat | 50.3 | 1.5 | 48.1 | 4.7 |
| MUFA | 10.2 | 2.5 | 8.6 | 0.6 |
| PUFA | 40.2 | 3.1 | 37.9 | 5.2 |
| n-3 | 3.4 | 0.8 | 4.8 | 1.2 |
| n-6 | 36.8 | 2.7 | 31.7 | 4.2* |
| n-3/n6 | 0.09 | 0.02 | 0.15 | 0.04* |
| unsat/sat | 1.01 | 0.06 | 0.94 | 0.16 |
| PUFA/MUFA | 4.15 | 0.96 | 4.58 | 0.64 |
| MUFA/sat | 0.20 | 0.05 | 0.20 | 0.08 |
| PUFA/sat | 0.81 | 0.08 | 0.74 | 0.15 |
Values are expressed as mole percentage and represent mean ± SD, n = 5–7. The * indicates a significant difference between groups, p<0.05.