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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Dev Biol. 2008 Jan 18;316(1):87–99. doi: 10.1016/j.ydbio.2008.01.006

Fig. 8. Inhibition of TACE also inhibits hair cell development.

Fig. 8

A: Experimental design of the TAPI-1 treatment of cochlear cultures. The explants were separated into control and 4 different treatment groups. DIV: days in vitro. B: Hair cell counts after treatment with various concentrations of TAPI-1 C, D: Explant cultures were treated with 100 µM TAPI-1 (C) or 20 µM TAPI-1 plus 5 µM DAPT (D), and stained with anti-Myo6. Error bars indicate standard deviations of the means. N= number of cochleas. Asterisk indicates P< 0.05, double asterisk indicate P< 0.005 compared to the control with a Student's T-test.