Table 1.
Clinical characteristics of type 2 diabetes patients and control volunteers
| Type 2 diabetes patients (n = 7) | Control volunteers (n = 7) | ||||
|---|---|---|---|---|---|
| Baseline | 4 h | 7 days | Baseline | 4 h | |
| Waist circumference (cm) | 101 ± 5 | 90 ± 6† | |||
| Metabolic syndrome | 6/7 | 0/7 | |||
| Systolic BP (mmHg) | 148 ± 12 | 146 ± 11 | 143 ± 7 | 135 ± 16 | 138 ± 12 |
| Diastolic BP (mmHg) | 78 ± 13 | 79 ± 13 | 82 ± 8 | 83 ± 9 | 85 ± 8 |
| Heart rate (beats per min) | 65 ± 9 | 67 ± 9 | 66 ± 12 | 61 ± 9 | 64 ± 8 |
| Total cholesterol (mmol/l) | 5.6 ± 0.4 | 6.5 ± 1.4 | 5.4 ± 1.3 | 5.3 ± 0.4 | 6.7 ± 1.3 |
| LDL-cholesterol (mmol/l) | 2.9 ± 0.6 | 3.3 ± 1.1 | 3.1 ± 1.0 | 3.0 ± 0.7 | 3.9 ± 1.2 |
| HDL-cholesterol (mmol/l) | 1.1 ± 0.2 | 2.7 ± 0.7* | 1.6 ± 0.6 | 1.2 ± 0.3 | 2.5 ± 0.4* |
| ApoA-I (g/l) | 1.2 ± 0.1 | 2.8 ± 0.4* | 1.5 ± 0.3 | 1.2 ± 0.2 | 2.7 ± 0.4* |
| Triacylglycerol (mmol/l) | 1.5 ± 0.4 | 1.6 ± 0.6 | 1.6 ± 0.5 | 0.8 ± 0.3† | 1.8 ± 1.3* |
| Glucose (mmol/l) | 8.3 ± 1.2 | 6.8 ± 1.7 | 7.3 ± 1.3 | 5.2 ± 0.4† | 4.9 ± 0.2 |
| hsCRP (mg/l) | 3.5 ± 1.6 | 4.4 ± 1.7 | 3.6 ± 0.8 | 1.0 ± 0.9† | 1.8 ± 1.1 |
| ASAT (U/l) | 22.5 ± 2.5 | 20.4 ± 4.0 | 22.4 ± 4.3 | 20.2 ± 1.8 | 21.4 ± 2.7 |
| ALAT (U/l) | 31.2 ± 6.9 | 26.0 ± 9.7 | 27.8 ± 8.7 | 14.9 ± 1.7† | 15.6 ± 3.2 |
| Basal FBF (ml 100 ml−1 FAV min−1) | 4.1 ± 2.0 | 3.7 ± 0.8 | 3.9 ± 1.3 | 2.6 ± 0.9 | 2.8 ± 0.7 |
Values are means ± SD
*p < 0.05 compared with baseline within one group; †p < 0.05 between type 2 diabetes and control volunteers ALT, alanine aminotransferase; ASAT, aspartate aminotransferase; hsCRP, high-sensitivity C-reactive protein