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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Placenta. 2008 Jan 11;29S:95–101. doi: 10.1016/j.placenta.2007.12.001

Figure 2.

Figure 2

Proteomic profiling of amniotic fluid and risk for preterm birth. A: Representative SELDI-TOF mass spectrometry profiles of amniotic fluid illustrating the biomarkers of the Mass Restricted (MR) score. The MR score enables a classification based on the “severity” of inflammation (MR=0 “no” inflammation; MR=2 “minimal” inflammation; MR=3–4 “severe” inflammation). CHCA and SPA denote the energy absorbing molecules α-cyano-4-hydroxycinnamic acid or sinnapinic acid, respectively. The CHCA chip allows for the identification of defensins 2 (P1: 3377.01 Da) and 1 (P2: 3448.09 Da). The SPA chip allows for identification of the peaks corresponding to calgranulin C (P3: 10,443.85 Da) and calgranulin A (P4: 10,834.51). The x axis of the tracings represents the molecular mass in Daltons; the y axis represents the relative peak intensity. B: Cumulative probability of pregnancy maintenance for the 169 patients illustrating the duration from amniocentesis-to-delivery in women with MR scores of 0 (zero), MR scores of 1–2, and MR scores 3–4.