Table 4.
Brain region (Brodman area) | x | y | z | T value | Z-score |
---|---|---|---|---|---|
NFPA | |||||
Left inferior frontal gyrus (44/45/47) | −48 | 15 | 25 | 8.2 | 7.1 |
−53 | 13 | 17 | 7.9 | 6.9 | |
−50 | 50 | −9 | 5.5 | 5.1 | |
Left precentral gyrus of the insula | −40 | 22 | 2 | 7.7 | 6.7 |
Left precentral sulcus/gyrus (4/6) | −43 | 4 | 49 | 7.9 | 6.8 |
−54 | −10 | 45 | 6.6 | 5.9 | |
−36 | −4 | 60 | 6.3 | 5.7 | |
Left middle frontal gyrus (8) | −38 | 20 | 48 | 7.5 | 6.6 |
Bilateral caudate nucleus | −11 | 12 | 5 | 6.7 | 6.0 |
16 | −4 | 20 | 5.9 | 5.4 | |
Left putamen | −22 | 10 | −3 | 5.8 | 5.3 |
SD | |||||
Bilateral amygdala/anterior hippocampus | −24 | −6 | −21 | 13.5 | Inf |
25 | −1 | −24 | 9.3 | 7.7 | |
Bilateral temporal pole (38/20/21) | −31 | −5 | −39 | 12.2 | Inf |
−36 | 17 | −42 | 9.7 | Inf | |
−48 | 14 | −22 | 9.9 | Inf | |
29 | −1 | −40 | 11.0 | Inf | |
29 | 16 | −37 | 9.7 | Inf | |
47 | 22 | −28 | 9.4 | 7.8 | |
Bilateral ant fusiform (37) | −40 | −20 | −26 | 10.2 | Inf |
44 | −20 | −28 | 6.1 | 5.5 | |
Bilateral middle temporal gyrus (21) | −64 | −10 | −18 | 9.5 | 7.8 |
−64 | −19 | −7 | 6.9 | 6.2 | |
68 | −12 | −16 | 7.9 | 6.9 | |
Bilateral posterior insula (long gyri) | −39 | −5 | 12 | 6.3 | 6.4 |
37 | −7 | 15 | 5.9 | 5.4 | |
Ventromedial frontal (25) | −1 | 11 | −10 | 6.1 | 5.5 |
Bilateral caudate nucleus | −9 | 3 | 15 | 7.4 | 6.5 |
12 | 0 | 15 | 6.2 | 5.6 | |
Right posterior thalamus | 6 | −15 | 13 | 6.1 | 5.6 |
LPA | |||||
Left inferior parietal lobule (39/40) | −45 | −54 | 49 | 7.8 | 6.8 |
−56 | −53 | 34 | 6.8 | 6.1 | |
−53 | −36 | 43 | 6.7 | 6.0 | |
−60 | −42 | 30 | 5.8 | 5.3 | |
Left middle temporal gyrus/superior temporal sulcus (21/22) | −68 | −24 | −3 | 7.3 | 6.4 |
−63 | −47 | 1 | 5.6 | 5.1 | |
Precuneus (31) | −8 | −54 | 47 | 7.2 | 6.4 |
Right angular gyrus (39) | 45 | −48 | 48 | 6.3 | 5.7 |
Left hippocampus | −27 | −10 | −16 | 6.1 | 5.6 |
VBM = voxel-based morphometry; NFPA = nonfluent progressive aphasia; SD = semantic dementia; LPA = logopenic progressive aphasia.