Table 4.

VBM Results: Each Group versus Controls

Brain region (Brodman area)	x	y	z	T value	Z-score
NFPA
Left inferior frontal gyrus (44/45/47)	−48	15	25	8.2	7.1
	−53	13	17	7.9	6.9
	−50	50	−9	5.5	5.1
Left precentral gyrus of the insula	−40	22	2	7.7	6.7
Left precentral sulcus/gyrus (4/6)	−43	4	49	7.9	6.8
	−54	−10	45	6.6	5.9
	−36	−4	60	6.3	5.7
Left middle frontal gyrus (8)	−38	20	48	7.5	6.6
Bilateral caudate nucleus	−11	12	5	6.7	6.0
	16	−4	20	5.9	5.4
Left putamen	−22	10	−3	5.8	5.3
SD
Bilateral amygdala/anterior hippocampus	−24	−6	−21	13.5	Inf
	25	−1	−24	9.3	7.7
Bilateral temporal pole (38/20/21)	−31	−5	−39	12.2	Inf
	−36	17	−42	9.7	Inf
	−48	14	−22	9.9	Inf
	29	−1	−40	11.0	Inf
	29	16	−37	9.7	Inf
	47	22	−28	9.4	7.8
Bilateral ant fusiform (37)	−40	−20	−26	10.2	Inf
	44	−20	−28	6.1	5.5
Bilateral middle temporal gyrus (21)	−64	−10	−18	9.5	7.8
	−64	−19	−7	6.9	6.2
	68	−12	−16	7.9	6.9
Bilateral posterior insula (long gyri)	−39	−5	12	6.3	6.4
	37	−7	15	5.9	5.4
Ventromedial frontal (25)	−1	11	−10	6.1	5.5
Bilateral caudate nucleus	−9	3	15	7.4	6.5
	12	0	15	6.2	5.6
Right posterior thalamus	6	−15	13	6.1	5.6
LPA
Left inferior parietal lobule (39/40)	−45	−54	49	7.8	6.8
	−56	−53	34	6.8	6.1
	−53	−36	43	6.7	6.0
	−60	−42	30	5.8	5.3
Left middle temporal gyrus/superior temporal sulcus (21/22)	−68	−24	−3	7.3	6.4
	−63	−47	1	5.6	5.1
Precuneus (31)	−8	−54	47	7.2	6.4
Right angular gyrus (39)	45	−48	48	6.3	5.7
Left hippocampus	−27	−10	−16	6.1	5.6

VBM = voxel-based morphometry; NFPA = nonfluent progressive aphasia; SD = semantic dementia; LPA = logopenic progressive aphasia.