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. 2000 Aug 17;83(6):725–728. doi: 10.1054/bjoc.2000.1330

Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cellines

A Parle-McDermott 1, P McWilliam 1, O Tighe 1, D Dunican 1, D T Croke 1
PMCID: PMC2363537  PMID: 10952775

Abstract

We have used serial analysis of gene expression (SAGE) to identify gene expression differences between a primary colon tumour cell line (SW480) and an isogenic lymph-node metastasis cell line (SW620). Differential expression was confirmed for the following genes: keratin K5, cystatin S, serum amyloid A, the human homologue of yeast ribosomal S28 and the p32 subunit of human pre-mRNA splicing factor SF2. Expression of confirmed differences were also analysed in other metastatic cell lines. © 2000 Cancer Research Campaign

Keywords: SAGE, colon, differential, metastasis, expression

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Selected References

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