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. 2002 Mar 18;86(6):1012–1016. doi: 10.1038/sj.bjc.6600167

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Copyright © 2002 Cancer Research UK

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DNA laddering in rats chronically treated with hrTNF-α (100 μg kg⁻¹ body weight/day). Lane 1: DNA molecular weight marker; lanes 2–5: 40 μg of gastrocnemius muscle DNA from control (lanes 2 and 3) and TNF-treated (lanes 4 and 5) rats respectively; lane 6: 20 μg of liver DNA from anti-Fas-treated mice (positive control) The percentage of DNA fragmentation was quantified by scanning densitometry.