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. 2002 Mar 18;86(6):1012–1016. doi: 10.1038/sj.bjc.6600167

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Copyright © 2002 Cancer Research UK

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DNA laddering in mice bearing the Lewis lung carcinoma. Lane 1: DNA molecular weight marker; lanes 2–5: 35 μg of gastrocnemius muscle DNA from wild-type control (lanes 2 and 3) and tumour-bearing (lanes 4 and 5) respectively; lanes 6–9: 35 μg of gastrocnemius muscle DNA from TNFRI KO mice, control (lanes 6 and 7) and tumour-bearing (lanes 8 and 9) respectively; lane 10: 20 μg of liver DNA from anti-Fas-treated mice (positive control) The percentage of DNA fragmentation was quantified by scanning densitometry.