Figure 7.

Lack of effect of anti-RyR1 (9 nmol per mouse i.c.v.), anti-RyR2 (7 nmol per mouse i.c.v.), anti-RyR3 (7 nmol per mouse i.c.v.), ryanodine (0.1 nmol per mouse i.c.v.), and 4-Cmc (9 nmol per mouse i.c.v.) on mouse spontaneous mobility (A) and exploratory activity (B) evaluated in the mouse hole board test, and on motor coordination (C) evaluated in the rota rod test. ODNs were administered once daily for 3 d. The test was performed 18 h after the last injection. Amphetamine (amph) was administered at the dose of 1 mg/kg s.c.; data are expressed as mean ± SEM; *P < 0.05 vs. control group.