Table 2.
SP-B | Pro-SP-B | SP-C | Pro-SP-C | ||||||
Western blot bands at (kDa) | 8 | 16–18 | 30 | 19–21 | 24–25 | 4.2 | 7 | 3–4 | 15–16 |
CF (n = 21) | 14 (67) | 21 (100) | 16 (76) | 4 (19) | 21 (100) | 19 (90) | 5 (26) | 2 (10) | 0 (0) |
Chronic bronchitis (n = 15) | 9 (60) | 15 (100) | 9 (60) | 2 (13) | 14 (93) | 15 (100) | 4 (26) | 0 (0) | 0 (0) |
Pneumonia (n = 14) | 4 (29) | 14 (100) | 6 (43) | 1 (7) | 12 (86) | 13 (100) | 2 (14) | 0 (0) | 0 (0) |
Healthy controls (n = 14 for SP-B (not shown) and pro-SP-B reduced, n = 4 for SP-B non-reduced) | 1 (25) | 4 (100) | 2 (50) | 2 (14) | 13 (93) | 14 (100) | 3 (21) | 0 (0) | 0 (0) |
Absolute rate of detection, in brackets %. Western blots for SP-B and SP-C under non-reducing conditions, for pro-SP-Band pro-SP-C under reducing condition. Frequencies were compared by Fisher's exact test and corrected for the comparisons made within each group of molecular weights. No significant differences were detected.