Table 6.
Rectal artemisinin | Non-rectal artemisinin comparator | Non-artemisinin comparator (quinine) | TOTAL | |
Total no. patients included in analysis | 786 | 253 | 123 | 1162 |
Total no. (%) of patients in whom one or more adverse event reported | 140 (18) | 24 (9) | 30 (24) | 194 |
Total no. of adverse events: | 196 | 43 | 67 | 306 |
Classification (aetiology): | ||||
Possibly drug-related | 37 | 14 | 27 | 78 |
Not likely to be drug related | 105 | 28 | 40 | 173 |
Unable to be classified | 54 | 1 | 0 | 55 |
Classification of possibly drug-related events according to body system: | ||||
Generalised | 11 | 1 | 0 | 12 |
Neurological | 1 | 1 | 7 | 9 |
Digestive | 18 | 10 | 8 | 36 |
Urogenital | 1 | 1 | 0 | 2 |
Haemopoetic | 3 | 1 | 4 | 8 |
Special senses (hearing) | 3 | 0 | 5 | 8 |
Other | 0 | 0 | 3 | 3 |