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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Dev Biol. 2008 Jan 3;315(1):217–231. doi: 10.1016/j.ydbio.2007.12.039

Fig. 3. Abnormal lens phenotype in the embryonic RhoGDIα transgenic mice.

Fig. 3

A. Hematoxylin and Eosin stained sagittal sections of E14.5 WT and RhoGDIα Tg eyes. The E14.5 Tg lenses from all three lines exhibit a marginal increase in size compared to wild type lenses. The magnification of WT and Tg lenses is the same. E14.5 lenses from Tg lines δ22 and δ91 show abnormal fiber cell morphology and defective secondary fiber cell organization. B. Higher magnification of E14.5 Tg lenses (white asterisks in panel A figures indicate the magnified area shown in panel B) at the equatorial region reveals defective fiber cell orientation and migration (indicated with arrows).