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. 2008 May 7;3(5):e2101. doi: 10.1371/journal.pone.0002101

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Time intervals a) from symptom onset in the index subject to randomization; b) from randomization to application of the intervention; c) from symptom onset to application of the intervention.