Figure 3. CagA's specification of photoreceptors requires SHP-2/CSW.
(A) Wild type larval eye discs contain thousands of photoreceptors, which were visualized by anti-ELAV staining. (B) Few photoreceptors develop in csw mutant larval eye discs. (C) Expression of UAS-CSW using GMR-GAL4 in the csw mutant partially rescued the lack of photoreceptor development but expression of UAS-CagA did not (D). (E) There was no significant difference (T-test, p value>0.2) in the number of photoreceptors (PR) that developed in csw mutants with or without CagA expression.