Table 1. Study subject characteristics by menopausal status at blood donation.
|
Premenopausal women |
Postmenopausal women |
|||
|---|---|---|---|---|
| Cases (n=189) | Controls (n=189) | Cases (n=228) | Controls (n=228) | |
| Age at blood donation, median (5–95th percentiles) | 44.2 (36.6–51.7) | 44.2 (36.3–52.0) | 58.8 (52.5–64.8) | 58.8 (52.5–65.0) |
| Age at diagnosis, median (5–95th percentiles) | 49.1 (40.1–57.0) | 64.2 (55.8–70.6) | ||
| Age at menarche, median (5–95th percentiles) | 12 (10–15) | 12 (10–16) | 13 (10–15) | 12 (10–15) |
| Nulliparous, n (%) | 73 (39%) | 58 (31%) | 57 (25%) | 47 (21%) |
| Age at first full-term pregnancy, median (5–95th percentiles)b | 25 (19–39) | 24 (18–36) | 25 (19–35) | 24 (19–34) |
| History of breast cancer in first-degree relatives, n (%)c | 51 (27%) | 25 (13%) | 43 (19%) | 51 (22%) |
| Total oophorectomy, n (%) | 0 | 0 | 29 (13%) | 25 (11%) |
| Ever used oral contraceptives, n (%) | 91/164 (55%) | 105/168 (63%) | 44/198 (22%) | 32/205 (16%) |
| Ever used hormone replacement therapy, n (%)d | 14/164 (9%) | 26/168 (15%) | 32/198 (16%) | 30/205 (15%) |
| Height (cm), median (5–95th percentiles) | 163 (152–175) | 163 (152–173) | 163 (152–173) | 163 (152–170) |
| Weight (kg), median (5–95th percentiles)e | 61.3 (49.0–84.0) | 61.3 (49.0–89.0) | 68.1 (51.8–89.9) | 63.6 (49.0–88.5) |
| Body mass index (kg m−2), median (5–95th percentiles)f | 23.0 (18.5–31.3) | 23.6 (19.0–32.5) | 25.7 (20.2–33.0) | 24.3 (19.7–32.5) |
| Energy intake (kcal), median (5–95th percentiles) | 1319 (720–2475) | 1359 (792–2510) | 1427 (807–2723) | 1491 (760–2549) |
| Percent energy from fat intake, median (5–95th percentiles) | 43.0 (30.2–51.7) | 42.2 (30.7–52.3) | 38.8 (28.2–50.7) | 39.2 (28.2–48.2) |
| Daily dietary fibre intake (g), median (5–95th percentiles) | 11.2 (4.5–23.0) | 10.9 (1.3–42.7) | 14.5 (1.9–51.6) | 14.3 (1.3–52.8) |
a
Unless specified, P-values were greater than 0.10.
b
P=0.08 in premenopausal women.
c
P=0.001 in premenopausal women.
d
P=0.05 in premenopausal women.
e
P=0.01 in postmenopausal women.
f
P=0.09 in postmenopausal women.