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. 2004 Jun 1;91(1):171–177. doi: 10.1038/sj.bjc.6601910

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Copyright © 2004 Cancer Research UK

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AdTRAIL induces caspase-dependent apoptosis in H460 cells. H460 cells were treated with AdTRAIL (MOI 10) in the presence or absence of zVAD-fmk, and after 3 days postinfection cell viability was determined (A). Values are the mean (n=3)±s.d., and P-values were determined by the Student's t-test. Western blot indicating the cleavage of procaspase-8 and PARP (B). Arrows indicate the cleaved products of PARP.