Table 1. Patients characteristics.

	E+P		E → P
	No.	%	No.	%
No. assessable	72		64
Median age (range)	58 (36–73)		58 (30–73)
Median ECOG PS	0 (0–1)		0 (0–1)
Disease status at random
Metastatic ab initio	19	26.4	10	15.7
Relapsed after surgery	53	73.6	54	84.3
Prior adjuvant CT	32	44.4	33	51.5
Epirubicin based	18	25	16	25

PS=perfofmance status; ECOG=European Collaborative Oncology Group; CT=chemotherapy