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. 2004 Jul 27;91(4):803–810. doi: 10.1038/sj.bjc.6602052

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Copyright © 2004 Cancer Research UK

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Effects of bisphosphonates on melanoma cell proliferation. A375 (A) and M186 (B) melanoma cells were incubated for 24 h with the indicated doses of pamidronate (squares) or zoledronate (circles). Cell proliferation was evaluated using the crystal violet technique. Four independent experiments were performed in quadruplicate with similar results. One representative experiment is shown. Results are given as % of controls±s.d. (n=4) (^*P<0.05; ^**P<0.01).