Table 2. c-erbB-1 mRNA expression and regression (sensitivity and specificity of response prediction).
|
Regression grading |
|||
|---|---|---|---|
| c-erbB-1a | Grades I/II (MiHRb) | Grades III/IV (MaHRc) | Total: n (%) |
| ⩽1: n (%) | 11 (30.6%) | 5 (13.9%) | 16 (44.4%) |
| >1: n (%) | 13 (36.1%) | 7 (19.4%) | 20 (55.6%) |
| Total: n (%) | 24 (66.7%) | 12 (33.3%) | 36 (100%) |
a
Dichotomised c-erbB-1 mRNA levels.
b
Minor histopathologic response.
c
Major histopathologic response.
Prediction of MiHR (c-erbB1>1): sensitivity 54.1%, specificity: 65% χ2-analysis (Fisher's exact test): P=1.