Table 3. c-erbB-1 mRNA expression and regression (sensitivity and specificity of response prediction for maximum cutoff).
|
Regression grading |
|||
|---|---|---|---|
| c-erbB-1a | Grades I/II (MiHRb) | Grades III/IV (MaHRc) | Total: n (%) |
| ⩽3.318: n (%) | 19 (52.8%) | 12 (33.3%) | 31 (86.1%) |
| >3.318: n (%) | 5 (13.9%) | ∅ | 5 (13.9%) |
| Total: n (%) | 24 (66.7%) | 12 (33.3%) | 36 (100%) |
a
Dichotomised c-erbB-1 mRNA levels.
b
Minor histopathologic response.
c
Major histopathologic response.
Prediction of MiHR (c-erbB1>3.32): sensitivity 20.8%, specificity: 100% χ2-analysis (Fisher's exact test): P=0.15.