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|
British trial |
German trial |
||||
|---|---|---|---|---|---|
| WHO | Carboplatin (%) | EP (%) | Carboplatin (%) | VIP (%) | |
| Maximum haematological toxicity | |||||
| Thrombocytopaenia | Grade 1/2 | 35 | 6 | 12 | 14 |
| Grade 3/4 | 9 | 8 | 6 | 27 | |
| Neutropaenia | Grade 1/2 | 69 | 63 | 34 | 14 |
| Grade 3/4 | 4 | 32 | 6 | 68 | |
| Maximum nonhaematological toxicity | |||||
| Nausea/vomiting | Grade 3/4 | 9 | 15 | 5 | 20 |
| Diarrhoea | Grade ⩾ 1 | 5 | 15 | 12 | 19 |
| Neurotoxicity | Grade ⩾ 1 | 0 | 11 | 2 | 14 |
| Ototoxicity | Grade ⩾ 1 | 0 | 15 | 3 | 3 |
