Skip to main content
. 2008 Apr 10;336(7651):1003–1006. doi: 10.1136/bmj.39532.543947.BE

Table 2.

 Proteinuria and diagnostic test characteristics for spot protein:creatinine ratio in hypertensive pregnant women

Study % (No) of women with proteinuria* Range of 24 hour proteinuria (g/day) Criteria for adequacy of 24 hour urine collection Timing of spot protein:creatinine ratio relative to 24 hour urine First voided morning urine tested Spot protein:creatinine ratio range (mg/mmol)
Al et al 2004w1 21 (39/185) 0-8.2† Urinary creatinine ≥10 mg/kg/day Before (morning) No 0-667†
Durnwald et al 2003w2 76 (168/220) 0-19† NS Before NS 0-2991
Jaschevatzky et al 1990w3 NS 0.1-9.7† NS After No 15.2-9552.5
Neithardt et al 2002w4 83 (25/30) 0.20-26.5 NS During (morning) NS 10-2124
Ramos et al 1999w5 55 (26/47) 0.24-22.3 Urinary creatinine >0.8 g/day Before NS NS
Robert et al 1997w6 41 (29/71) 0.03-12.6 NS During No NS
Rodriguez-Thompson et al 2001w7 50 (69/138) 0-2† NS Before No 0-170†
Saudan et al 1997w8 NS NS NS Before (usually morning) No NS
Taherian et al 2006w9 73 (73/100) 0.1-8.2† NS Before No 33.9-9186.9
Valerio et al 2005w10 51 (38/75) 0-15† Urinary creatinine ≥0.6 g/day Before (serially§) NS 0-9200†
Wheeler et al 2007w11 54 (68/126) 0.06-10.8 Urinary creatinine >1 g/day with urine volume >1 l/day Before No 1.1-1661
Yamasmit et al 2004w12 69(29/42) 0.70-6.3 NS Before No 8-741
Young et al 1996w13 58 (26/45) 0.10-0.8† Maternal report Before (66%), after (34%) No 8-103†

NS=not specified.

*0.3 g/day or more.

†Range abstracted from figure.

‡Urinary catheter was used in 89% of women because they had vaginal bleeding, were post partum, were in active labour, or were taking magnesium sulphate.

§At 8 am to 2 pm, 2 pm to 8 pm, 8 pm to 2 am, and 2 am to 8 am.