Table 2.
Proteinuria and diagnostic test characteristics for spot protein:creatinine ratio in hypertensive pregnant women
Study | % (No) of women with proteinuria* | Range of 24 hour proteinuria (g/day) | Criteria for adequacy of 24 hour urine collection | Timing of spot protein:creatinine ratio relative to 24 hour urine | First voided morning urine tested | Spot protein:creatinine ratio range (mg/mmol) |
---|---|---|---|---|---|---|
Al et al 2004w1 | 21 (39/185) | 0-8.2† | Urinary creatinine ≥10 mg/kg/day | Before (morning) | No | 0-667† |
Durnwald et al 2003w2† | 76 (168/220) | 0-19† | NS | Before | NS | 0-2991 |
Jaschevatzky et al 1990w3 | NS | 0.1-9.7† | NS | After | No | 15.2-9552.5 |
Neithardt et al 2002w4 | 83 (25/30) | 0.20-26.5 | NS | During (morning) | NS | 10-2124 |
Ramos et al 1999w5 | 55 (26/47) | 0.24-22.3 | Urinary creatinine >0.8 g/day | Before | NS | NS |
Robert et al 1997w6 | 41 (29/71) | 0.03-12.6 | NS | During | No | NS |
Rodriguez-Thompson et al 2001w7 | 50 (69/138) | 0-2† | NS | Before | No | 0-170† |
Saudan et al 1997w8 | NS | NS | NS | Before (usually morning) | No | NS |
Taherian et al 2006w9 | 73 (73/100) | 0.1-8.2† | NS | Before | No | 33.9-9186.9 |
Valerio et al 2005w10 | 51 (38/75) | 0-15† | Urinary creatinine ≥0.6 g/day | Before (serially§) | NS | 0-9200† |
Wheeler et al 2007w11 | 54 (68/126) | 0.06-10.8 | Urinary creatinine >1 g/day with urine volume >1 l/day | Before | No | 1.1-1661 |
Yamasmit et al 2004w12 | 69(29/42) | 0.70-6.3 | NS | Before | No | 8-741 |
Young et al 1996w13 | 58 (26/45) | 0.10-0.8† | Maternal report | Before (66%), after (34%) | No | 8-103† |
NS=not specified.
*0.3 g/day or more.
†Range abstracted from figure.
‡Urinary catheter was used in 89% of women because they had vaginal bleeding, were post partum, were in active labour, or were taking magnesium sulphate.
§At 8 am to 2 pm, 2 pm to 8 pm, 8 pm to 2 am, and 2 am to 8 am.