FIG. 2.
Severity of keratitis in rabbits infected with McKrae strain HSV-1 in both eyes and treated topically with BAY 57-1293 2% suspension of cremophor or cyclodextrin, 1% trifluridine, or balanced salt solution (BSS) on postinjection days 3-7. Severity was graded on a masked basis on a scale of 1-4. (A) BAY 57-1293 was solubilized in cremophor and diluted in BSS and administered twice a day. (B) BAY 57-1293 was solubilized in cyclodextrin and diluted in BSS and administered twice or four times a day.