Table 1.

Genotypes of Aurora-A and p16 and their association with risk for early diagnosis of pancreatic cancer

Genotype	n (%), N = 148	Median age at diagnosis (y)	P*	HR (95% CI)
Aurora-A (T→A)
TT	101 (68.2)	62.4	0.015	1.00 (reference)
TA/AA	47 (31.8)	59.6		1.55 (1.09–2.20)
p16 C540G (C→G)
CC	107 (72.3)	60.4	0.252	1.00 (reference)
CG/GG	41 (27.7)	61.4		0.80 (0.56–1.17)
p16 C580T (C→T)
CC	120 (81.1)	62.1	0.050	1.00 (reference)
CT/TT	28 (18.9)	58.9		1.52 (1.00–2.30)

^*Log-rank test for homogeneity between genotypes.