Table 2.
Regional Changes in Gray Matter Density Between OCD Patients and Healthy Control Subjects*
| Coordinates | Statistic | ||||
|---|---|---|---|---|---|
| OCD > Siblings | X | Y | Z | Z Score | p (FDR-corr)1 |
| Right Putamen | 31 | 4 | 0 | 3.99 | 0.04 |
| Right Putamen | 32 | 0 | 3 | 3.85 | 0.04 |
| OCD < Control | X | Y | Z | Z Score | p (FDR-corr)2 |
| Left Anterior Cingulate Gyrus | −8 | 46 | 3 | 4.43 | 0.01 |
| Right Medial Superior Frontal Gyrus | 12 | 50 | 15 | 3.51 | 0.01 |
| Left Medial Superior Frontal Gyrus | −4 | 63 | 12 | 3.91 | 0.01 |
OCD > Controls and OCD < Siblings did not demonstrate any significant differences.
Based on small volume correction and
main comparison.