Table 1.
1H NMR Data of Compounds 1–6 (in DMSO-d6, 500 MHz, δppm).
| position | 1 | 2 | 3 | 4 | 5 | 6 |
|---|---|---|---|---|---|---|
| 1 | 12.19 | 11.52 | ||||
| (br s) | (br s) | |||||
| 2 | 8.45 | 8.44 | 8.22 | 8.69 | 8.68 | 7.86 |
| (d, J=2.0 Hz) | (s) | (s) | (s) | (s) | (s) | |
| 4 | 8.07 | 8.16 | 7.82 | 8.22 | 8.12 | 7.74 |
| (d, J=8.0 Hz) | (d, J=7.0 Hz) | (d, J=8.0 Hz) | (d, J=6.0 Hz) | (d, J=8.5 Hz) | (d, J=8.5 Hz) | |
| 5 | 7.40 | 7.27 | 6.74 | 7.25 | 7.36 | 6.68 |
| (dd, J=8.0, 2.0 Hz) | (t, J=7.0 Hz) | (dd, J=8.0, 2.0 Hz) | (t, J=6.0 Hz) | (dd, J=8.5, 2.0 Hz) | (dd, J=8.5, 2.0 Hz) | |
| 6 | 7.30 | 7.25 | ||||
| (t, J=7.0 Hz) | (t, J=6.0 Hz) | |||||
| 7 | 7.73 | 7.55 | 6.87 | 7.52 | 7.70 | 6.81 |
| (d, J=2.0 Hz) | (d, J=7.0 Hz) | (d, J=2.0 Hz) | (d, J=6.0 Hz) | (d, J=2.0 Hz) | (d, J=2.0 Hz) | |
| -OCH3 | 3.89 | 3.90 (s) | 3.87 | 3.76 | ||
| (s) | (s) | (s) | ||||
| -NH2 | 8.06 | 8.05 | ||||
| (br s) | (br s) | |||||
| 7.69 | 7.67 | |||||
| (br s) | (br s) | |||||
| -OH | 9.17 | |||||
| (br s) |