Fig. 2.
The mutational frequencies of MNU (A), MNNG (B), MMS (C), ENU (D), ENNG (E) and EMS (F) in a MutS-deficient strain (filled circle) or wild-type (open circle). *P < 0.05, **P < 0.01 compared to the mutant frequency for the wild-type. Three to six independent experiments were performed for each. Mutational frequencies were obtained after correcting for the frequency of spontaneous mutations. The frequencies of spontaneous mutations are (34.3 ± 3.3) × 10−7 for the MutS (−) strain (NR12986) and (0.3 ± 0.1) × 10−7 for the wild-type strain (NR10832).
