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. Author manuscript; available in PMC: 2008 May 2.
Published in final edited form as: Clin Infect Dis. 2007 Mar 9;44(8):1115–1122. doi: 10.1086/512816

Table 5.

Ten-year and lifetime projected outcomes for untreated and treated cohorts per 1 million population.

Variable Untreated cohort Treated cohort
Survival
 Mean months 145.4 366.7
 Median months (range) 139.5 (1–544.5) 381.5 (1–969.5)
10 Years after infection
 No. (%) of secondary cases, by HIV RNA level
  0–500 copies/mL 8566 (0.5) 45,241 (3.2)
  501–3000 copies/mL 198,007 (10.3) 153,472 (11.0)
  3001–10,000 copies/mL 323,905 (16.9) 231,665 (16.5)
  10,001–30,000 copies/mL 359,459 (18.8) 243,213 (17.4)
  >30,000 copies/mL 570,457 (29.8) 365,328 (25.8)
 Primary infection 361,432 (18.9) 361,432 (25.8)
 Late-stage infectiona 91,939 (4.8) 90 (0)
R010 1.9 1.4
Lifetime of infection
 No. (%) of secondary cases, by HIV RNA level
  0–500 copies/mL 15,939 (0.6) 196,152 (6.4)
  501–3000 copies/mL 315,702 (12.6) 407,083 (13.2)
  3001–10,000 copies/mL 443,663 (17.7) 574,445 (18.7)
  10,001–30,000 copies/mL 444,081 (17.7) 577,609 (18.8)
  >30,000 copies/mL 643,729 (25.7) 843,084 (27.4)
 Primary infection 361,432 (14.4) 361,432 (11.8)
 Late-stage infectiona 278,107 (11.1) 114,846 (3.7)
R0 2.5 3.1
a

Once an individual is defined as having late-stage infection, they are no longer counted in any of the CD4+ cell count strata.