Fig. 2.

Characterization of HER2-specific binding. a Representative results of competition-binding assay using SKOV-3 cells (log of concentration of competitor compound versus percent of the maximum specific binding of radiolabeled Affibody molecule). b Representative results of saturation assay using SKOV-3 cells (concentration of radiolabeled Affibody molecule versus concentration bound: NSB non-specific binding obtained by saturation of the receptors with 100-fold excess of non-labeled Affibody, TB total binding, and SB specific binding)