Fig. 4.
a The [18F]FBEM-ZHER2:432-Affibody uptake 2 h post i.v. injection in athymic nude mice bearing either HER2-positive SKOV-3 cells after pretreatment with or without non-radioactive Affibody or HER2-negative U251 tumors (tissue type versus % ID/g tissue). Each bar represents an average ± SD from n = 3-6. b Blood kinetics of [18F]FBEM-ZHER2:342-Affibody. The squares represent % ID/g in the blood with an exponential curve fit. Insert Average HMW fractions of the plasma-associated radioactivity. Each point represents mean ± SD (three to four mice)