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. 2007 Dec 22;35(5):1008–1018. doi: 10.1007/s00259-007-0658-0

Table 1.

Biodistribution of [18F]FBEM-ZHER2:342-Affibody in mice bearing SKOV-3 xenografts

Organ % ID/g 1 h 2 h 3 h 4 h 6 h
Blood 1.31 ± 0.75 0.28 ± 0.04 0.25 ± 0.09 0.09 ± 0.03 0.16 ± 0.08
Heart 0.93 ± 0.22 0.14 ± 0.02 0.07 ± 0.01 0.05 ± 0.02 0.06 ± 0.01
Lungs 2.85 ± 0.65 0.46 ± 0.27 0.34 ± 0.12 0.28 ± 0.07 0.23 ± 0.03
Kidney 14.08 ± 0.05 4.17 ± 1.41 2.36 ± 0.11 1.53 ± 0.80 1.43 ± 0.29
Spleen 2.05 ± 0.52 0.23 ± 0.09 0.17 ± 0.02 0.11 ± 0.06 0.15 ± 0.04
Liver 5.04 ± 0.69 0.88 ± 0.51 0.68 ± 0.18 0.33 ± 0.08 0.41 ± 0.05
Pancreas 0.80 ± 0.16 0.10 ± 0.04 0.07 ± 0.03 0.08 ± 0.05 0.06 ± 0.01
Tumor 9.73 ± 1.91 6.36 ± 1.26 6.95 ± 0.93 6.22 ± 1.25 6.80 ± 0.01
Bone 2.15 ± 0.40 2.07 ± 0.37 2.27 ± 0.27 1.28 ± 0.64 0.60 ± 0.04
Brain 0.08 ± 0.01 0.02 ± 0.01 0.02 ± 0.01 0.01 ± 0.01 0.02 ± 0.01
Stomach 1.02 ± 0.13 0.16 ± 0.03 0.44 ± 0.52 0.08 ± 0.01 0.10 ± 0.05
Sm. intestine 2.26 ± 1.73 0.11 ± 0.04 0.30 ± 0.21 0.24 ± 0.17 0.51 ± 0.30
Muscle 0.46 ± 0.05 0.06 ± 0.02 0.06 ± 0.01 0.02 ± 0.01 0.05 ± 0.01

Numbers represent mean uptake expressed in % ID/g ± SD (n = 3-6).