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. Author manuscript; available in PMC: 2008 May 2.
Published in final edited form as: Neurosci Lett. 2007 Jun 14;422(3):158–163. doi: 10.1016/j.neulet.2007.05.061

Fig. 2.

Fig. 2

Immunohistochemical localization of IRP1 and IRP2 in the brains of control and scrapie-infected mice. Intense immunolabeling of IRP1 and IRP2 appear in the hippocampus and cerebral cortex of scrapie-infected mice. Black arrows: vacuoles, white arrows: immunolabeled cells with IRP1 (B and E) and IRP2 (H and K). In (C, F, I and L) white arrows indicate immunolabeling of GFAP and black arrows indicate vacuoles. In sequential sections, immunoreactivity of IRP1 and IRP2 is colocalized with GFAP-positive reactive astrocytes. Sequential sections are B and C, E and F, H and I, K and L. Asterisk (*) indicates landmark blood vessels in the adjacent tissue section.