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. Author manuscript; available in PMC: 2008 May 2.
Published in final edited form as: Am J Ophthalmol. 2007 Feb 5;143(4):607–615. doi: 10.1016/j.ajo.2006.12.006

FIGURE 2.

FIGURE 2

Select redox proteins in Minnesota Grading System (MGS) stages of age-related macular degeneration (AMD); antioxidant enzyme content. Retinal pigment epithelial (RPE) proteins (15 μg) were subjected to sodium dodecyl sulphate polyacrylamide gel electrophoresis followed by Western immunoblotting. Data were normalized to a standard reaction in all blots and to heat shock protein 70 (HSP70) as a loading control (LC). Individual donor relative densities from four age groups are shown (gray symbols). Group mean ± standard error of the mean (SEM) and the results of linear regression analysis are shown. n = 5–7 donors/stage. Inset shows representative Western immunoblot of antioxidant enzymes catalase (Top), manganese superoxide dismutase (MnSOD) (Middle), and copper-zinc superoxide dismutase (CuZnSOD) (Bottom) at MGS 1–4 and the LC-HSP70.