Table 3.
Perinatal, Infant Death, and Small-for-Gestational-Age in Singletons Born of Untreated Couples According to Time to Pregnancy
| Perinatal deaths
|
Infant deaths (8–365 days)
|
Small-for-gestational-age* |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of singletons |
No. (mortality, 1/1000) |
Crude OR (95% CI) | Adjusted OR† (95% CI) |
Adjusted OR‡ (95% CI) |
No. (mortality, 1/1000) |
Crude OR (95% CI) | Adjusted OR† (95% CI) |
Adjusted OR‡ (95% CI) |
No. (%) |
Crude OR (95% CI) | Adjusted OR§ (95% CI) |
Adjusted OR|| (95% CI) |
|
| Time to pregnancy (months) | |||||||||||||
| 0–2 | 28,110 | 132 (4.7) | 1.00 Ref | 1.00 Ref | 1.00 Ref | 42 (1.5) | 1.00 Ref | 1.00 Ref | 1.00 Ref | 1169 (4.2) | 1.00 Ref | 1.00 Ref | 1.00 Ref |
| 3–5 | 13,138 | 74 (5.6) | 1.20 (0.90–1.60) | 1.18 (0.88–1.57) | 1.15 (0.87–1.54) | 18 (1.4) | 0.92 (0.53–1.59) | 0.91 (0.53–1.59) | 0.94 (0.54–1.64) | 572 (4.4) | 1.05 (0.95–1.16) | 1.04 (0.94–1.15) | 1.00 (0.90–1.10) |
| 6–12 | 9,793 | 47 (4.8) | 1.02 (0.73–1.43) | 0.98 (0.70–1.37) | 0.95 (0.68–1.33) | 17 (1.7) | 1.16 (0.66–2.04) | 1.16 (0.66–2.04) | 1.22 (0.69–2.14) | 459 (4.7) | 1.13 (1.01–1.27) | 1.10 (0.98–1.23) | 1.03 (0.92–1.15) |
| >12 | 5,787 | 42 (7.3) | 1.55 (1.09–2.20) | 1.39 (0.97–1.97) | 1.32 (0.93–1.88) | 9 (1.6) | 1.04 (0.51–2.15) | 1.09 (0.53–2.26) | 1.18 (0.57–2.44) | 345 (6.0) | 1.47 (1.30–1.66) | 1.38 (1.22–1.56) | 1.25 (1.10–1.42) |
| P for trend | 0.054 | 0.19 | 0.30 | 0.73 | 0.67 | 0.51 | <0.001 | <0.001 | 0.005 | ||||
Logistic regression; OR: odd ratios; CI: confidence interval.
Among live births.
Adjusted for maternal age, and pre-pregnancy body mass index.
Adjusted for maternal age, pre-pregnancy body mass index, and parity.
Adjusted for maternal age, and smoking.
Adjusted for maternal age, smoking, and parity.