Table 4.
Small-for-Gestational-Age Singletons According to Parental Infertility and Treatment
| Reference: Group A
|
Reference: Group B
|
|||||||
|---|---|---|---|---|---|---|---|---|
| No. of singletons | No. of small-for-gestational-age (%) | Crude OR (95% CI) | Adjusted OR* (95% CI) | Adjusted OR† (95% CI) | Crude OR (95% CI) | Adjusted OR* (95% CI) | Adjusted OR† (95% CI) | |
| Group A: | ||||||||
| Fertile couples | 50614 | 2200 (4.3) | 1.00 Ref | 1.00 Ref | 1.00 Ref | |||
| Group B: | ||||||||
| Infertile couples conceiving naturally | 5722 | 345 (6.0) | 1.41 (1.26–1.59) | 1.33 (1.18–1.50) | 1.24 (1.10–1.40) | 1.00 Ref | 1.00 Ref | 1.00 Ref |
| Group C: | ||||||||
| Infertile couples receiving treatment | 4271 | 304 (7.1) | 1.69 (1.49–1.91) | 1.78 (1.56–2.02) | 1.40 (1.23–1.60) | 1.19 (1.02–1.40) | 1.31 (1.11–1.54) | 1.14 (0.96–1.35) |
| ICSI | 396 | 30 (7.6) | 1.80 (1.24–2.62) | 1.94 (1.33–2.82) | 1.40 (0.96–2.05) | 1.28 (0.87–1.88) | 1.43 (0.97–2.12) | 1.14 (0.77–1.70) |
| IVF | 1474 | 93 (6.3) | 1.48 (1.20–1.84) | 1.58 (1.27–1.96) | 1.17 (0.94–1.46) | 1.05 (0.83–1.33) | 1.16 (0.91–1.48) | 0.95 (0.74–1.22) |
| IUI | 1322 | 103 (7.8) | 1.86 (1.51–2.28) | 1.96 (1.59–2.41) | 1.57 (1.27–1.94) | 1.32 (1.05–1.66) | 1.45 (1.15–1.83) | 1.27 (1.00–1.61) |
| HT | 1079 | 78 (7.2) | 1.71 (1.36–2.17) | 1.75 (1.39–2.22) | 1.52 (1.20–1.93) | 1.21 (0.94–1.57) | 1.31 (1.01–1.69) | 1.22 (0.94–1.58) |
Logistic regression; OR: odd ratios; CI: confidence interval; ICSI: intracytoplasmic sperm injection; IVF: in vitro fertilization; IUI: intrauterine insemination; HT: hormonal treatment.
Adjusted for maternal age, and smoking.
Adjusted for maternal age, smoking, and parity.