TABLE 1.
Treatment | MyD88 KO Alive cells (%) | B6/129 MΦ Alive cells (%) | MyD88 KO B7.2+CD40High (%) | B6/129 MΦ B7.2+CD40High (%) |
---|---|---|---|---|
mDF2β | 83 ± 1.84 | 49.3 ± 0.8a | 27.7 ± 1.7 | 37.04 |
LPS 10 ng/ml | 86.2 ± 0.1 | 67.3 ± 0.2 | 22.6 ± 0.8 | 27.91 |
sFv315 | 80.7 ± 0.5 | 84.3 ± 4.2 | 19.7 ± 0.5 | 16.1 |
CM | 80.6 ± 0.1 | 80.6 ± 0.3 | 21.2 ± 0.9 | 15.4 |
Immortalized macrophage cells from wt mice B6/129 [B6/129 macrophage (MΦ)] or MyD88 KO mice, treated with mDF2β, sFv315, or LPS, were stained for cell survival and maturation (B7.2+CD40High markers) as in Figure 3.
P < 0.001 is for comparisons of pooled data of mDF2β with sFv315. Data are from two independent, triplicate experiments.