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A hypothetical graph showing the relation between spinal or cranial pressure, and venous volume, with and without Chiari malformation. CSF obstruction at the foramen magnum divides the CSF space into cranial and spinal compartments. The sum of the pressure volume indices of the two spaces would approximate that of the unobstructed CNS. The pressure response to influx of venous volume either in the head or the spine may be enhanced by the presence of Chiari malformation.
